Petra Lutterbuese

Principal Scientist Amgen

Seminars

Thursday 9th July 2026
Preclinical Safety Assessment of Dual ‘AND’ TCEs: Challenges in Selecting Good Target Pairs
11:30 am
  • Preclinical development of a dual-targeting T-cell Engager (TCE) – AMG 305
  • Leveraging different techniques in a weight of evidence (WoE) approach to uncover target co-localisation in normal human tissues
  • Challenges with relevant species determination for AND-gated targets
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