Fireside Chat: How Can We Predict Clinical Reality Through Preclinical Models & Translational Strategies?

12:00 pm - Wednesday 8th July 2026

  • Which preclinical models have proven most predictive for bispecifics, TCEs, and ADCs- including safety and immunogenicity risk, and which consistently fail to translate?
  • How do teams combine in vitro, in vivo, and computational approaches to reduce uncertainty before first-in-human studies?
  • What translational signals provide sufficient confidence to advance a program, and how do teams actively manage remaining risk?

Speakers:

Senior Principal Scientist - Immunosafety
Roche
Founder & Chief Executive & Scientific Officer
Adaptam Therapeutics