A Translational Approach to Evaluate T Cell Engagers and Bispecific Antibodies in Humanized Animal Models
- Development of Co-inoculated tumor/PBMC animal models to assess the efficacy and immune-mediated mechanisms of T Cell Engagers and Bispecific Antibodies.
- Application of a humanized MiniPDX platform to evaluate bispecifics in fresh patient-derived samples.
- Establishment of clinically relevant animal models to support candidate selection and optimization